Flights from Madrid to Panama City

Find direct and indirect flights from Madrid to Panama City (Panama) with eDreams. Once you have your results, sort them by schedule or price and book the option that best suits your plans.

The lowest fare booked on this route in recent days was €265, though the price you see will depend on your travel dates and departure times.

A direct flight from Madrid to Panama City takes around 10 h and 35 m, while indirect flights will take longer.

Knowing where you set off from and where you arrive helps you organise your journey better. Consider the available airports and compare the different airlines operating on this route.

• Departure airport: Adolfo Suárez Madrid - Barajas Airport (MAD)
• Arrival airport: Tocumen International Airport (PTY)

The best time to visit may depend on your preferred climate. In Panama City, the average temperature floats around 35ºC in the warmest months and 18ºC in the coldest ones. Keep this in mind when packing and planning any outdoor activities.

• Highs: up to 35ºC
• Lows: down to 18ºC
• Hottest month: April
• Coldest month: February
• Driest month: February
• Wettest month: October

A few tips for finding cheaper flights from Madrid to Panama City:

• Flexible dates: compare fares for two or three different departure days. Leaving a day earlier or later can make a noticeable difference to the price.
• Baggage allowance: check what each fare includes before you book, so you aren't caught out by extra charges at the airport.
• Airports on your route: confirm which airports you depart from and land at, especially if the city has more than one. This will help you plan your transfer and work out the total cost of getting around.

Looking for a bigger saving? Book a Flight + Hotel package to combine both in one booking and unlock exclusive discounts on your stay in Panama City. You can also save on a hire car by including it with your booking.